Tuesday, April 8, 2014

Historical Contribution: HH Young, Interstitial Radiotherapy, 1917

1917

Interstitial Radiotherapy:  The use of radium and the punch operation in desperate cases of enlarged prostate.  Young H.H.  Ann Surg. 1917;65:633-41.

The idea of brachytherapy, or inserting radioactive implants directly into tissue, was first proposed by Pierre Curie in 1901.  Intraurethral radium was used by Pasteau and Degrais in 1914 and the first prostate brachytherapy was administered transperineally in 1917 by Barringer.

In the same year, 1917, at Johns Hopkins Hospital, Hugh Hampton Young reported a series of patients treated with radium needles implanted transperineally, transrectally, and transurethrally.[1]  In the manuscript featured in this entry, Dr. Young "determined to attempt to cause atrophy of the prostate and shrinking of the intravesical lobes by simple means-radium and fulguration-and the history will show that this was remarkably successful."

He noted "a remarkaible shrinking of the hypertrophied gland, with the peculiar tissue changes ... but also without complete relief of obstruction, which generally has remained unchanged, so that radium alone is apparently not a cure for prostatic hypertrophy."  Therefore Dr. Young coupled the radiation treatments with his "punch" procedure to treat his patients.  While radiation treatment fell out of favor for the treatment of benign prostatic diseases, Young astutely predicted that
"in radium we undoubtedly have a therapeutic agent of great value in urology and with improved apparatus... many brilliant results should be obtainable."

In addition to those observations, take note of the scientific precision with which Dr. Young administered the radium, the devices he created to administer the doses safely and diligence with which he recorded clinical outcomes.

Read the entire manuscript here.




[1] Young HH, Fronz W (1917) Some new methods in the treatment of carcinoma of the lower genitourinary tract with radium. J Urol 1: 505–536

4 comments:

  1. God bless Dr.Ekpiku for his marvelous work in my life, my name is Joyce Benson from USA, I was diagnosed of HERPES since 2013 and I was taking my medications, I wasn't satisfied i needed to get the HERPES out of my system, I searched about some possible cure for HERPES i saw a comment about Dr Ekpiku how he cured HERPES with his herbal medicine, I contacted him and he guided me. I asked for solutions, he started the remedy for my health, he sent me the medicine through UPS delivery company. I took the medicine as prescribed by him and 11 days later i tested negative for HERPES, Dr.Ekpiku truly you are great, do you need his help also? Why don't you contact him through email (ekpikuspellhomeofgrace@gmail.com) or call him on +2348073673757 and you can also contact me to know more about him on my email Joycebenson731@gmail.com or text me +16506538578. DOCTOR Ekpiku CAN AS WELL CURE THE FOLLOWING DISEASE:- 1. HIV/AIDS 2. HERPES 3. CANCER 4. ALS 5. Hepatitis B 6. Diabetes 7. Athrux, 8. hydrophobia 9.hpv 10 pregnancy spell and bring back your ex back 11 scabies 12. STD.

    ReplyDelete
  2. I’m Mark Russ , I contracted HIV in 2009, I was told by my doctor that
    there’s no possible cure for HIV. I started taking my ARV’s, My CD4 was 77
    and viral load was 112,450. I saw a website of Dr. Imoloa also I saw a lot
    of testimonials about him on how he uses herbal medicine to cure HIV. I
    contacted him and told him my problems, He sent me the herbal medicine and
    I took it for 7 days after then I went for check-up and I was cured. The
    medicine has NO SIDE EFFECT, there’s no special diet when taking the
    medicine. He also cure DIABETES, EX BACK, ALS, HEPATITIS B, CANCER, HERPES
    1) If you want your ex back.
    (2) If you always have bad dreams.
    (3) You want to be promoted in your
    office.
    (4) You want women/men to run after
    you.
    (5) If you want your own children
    (6) You want to be rich.
    (7) You want to tie your husband/wife to
    be
    yours forever.
    (8) If you need financial assistance.
    (9) How you been scammed and you
    (10) and if you ant your herpes cure back
    want to recover you lost money
    (11) CANCER,
    (12) DIABETES,
    (13) HIV&AIdS,
    (14) URINARY TRACT INFECTION,
    (15) CANCER,
    (16) IMPOTENCE,
    (17) BARENESS/INFERTILIY
    (18) DIARRHEA
    (19) ASTHMA..
    Also contact him with the above.
    and lots more. You can reach him on drimoloaherbalmademedicine@gmail.com or
    Whatsapp +2347081986098 all thanks to dr imoloa he is really a great man .

    ReplyDelete
  3. i am from USA, i am here to give my testimony how i was cured from HIV, i
    contacted my HIV via blade. a friend of my use blade to peel of her
    finger nails and drop it where she use it, so after she has left i did know
    what came unto me i looked at my nails, my nails were very long and i took
    the blade which she just used on her own nails to cut of my finger nails,
    as i was maintaining my names, i mistakenly injured myself. i did even
    bothered about it, so when i got to the hospital the next week when i was
    ill the doctor told me that i am HIV positive, i wondered where did i got
    it from so i remembered how i use my friend blade to cut off my hand so i
    feel so sad in my heart to the extent that i don’t even know what to do, so
    one day i was passing through the internet i met a testimony of a lady that all
    talk about how she was cured by a doctor called DR Imoloa so i quickly
    emailed the doctor email, and he also replied to me an told me the
    requirements which i will provide and I do according to his command,
    he prepare a herbal medicine for me which i took. he
    called me the next week that i should go for a test which i did to my own
    surprise i found that i was HIV negative. Thanks to him once more the great
    doctor that cured me DR Imoloa so you can also emailed him at
    {drimoloaherbalmademedicine@gmail.com} or whatssapp him on +2347081986098} God Bless you Sir.

    ReplyDelete
  4. I found out, that taking herbal treatment is the best to get rid of hpv as soon as i feel the symptoms of hpv is appearing, i took the healing process by contacting Dr onokun for natural treatment it works wonders, amazingly ever since I had the herbal treatment i have not feel these horrible disease anymore and my doc told me the virus is gone, i am glad i finally got cured out from this horrible disease. every hpv or herpes patients should also get in touch with this herbalist Dr to get ride of these disease forever his email address;
    dronokunherbalcure@gmail.com

    ReplyDelete