Wednesday, March 12, 2014

BCG Complications for Bladder Cancer: Who, What, When and How to Treat?

Bacillus Calmette-Guérin (BCG) immunotherapy currently remains the most effective treatment for intermediate and high risk non-muscle-invasive bladder cancer, but has side effects that range from bothersome to life-threatening. To learn more about BCG treatment, please see our prior blog on the "Success Rates for Intravesical BCG Treatments for Bladder Cancer."

Here we review the common BCG side effects, the prevention and treatment of these effects.

Common BCG Side Effects:

  • Mild Urinary Symptoms (5-90%) [1,2]
    • Frequency
    • Dysuria
    • Hematuria (1-34%) [2]
  • Malaise (Fatigue)
  • Fever (3-17%) [3-5]
BCG works through a local immune response, therefore some side effects and indicative of BCG effectiveness.  In fact, fever has been reported to correlate with a reduction in the risk of recurrence; however, many patients have no symptoms from BCG and remain tumor free.

Patients should be instructed to expect mild urinary frequency and dysuria beginning after the second or third instillation. These symptoms should last only a few days and should not be disabling. Mild malaise, fatigue, and “flu-like” symptoms similar to those following a vaccination are seen less frequently, likely a consequence of immune stimulation and not generally of concern.

Unexpected or severe symptoms are often associated with increasing symptoms with successive instillations.

How to treat mild symptoms & side effects:

  • Treatment for mild symptoms can include:
    • phenazopyridine hydrochloride
    • acetaminophen 
    • nonsteroidal anti-inflammatory drugs
  • If the side effects are tolerable (not increasing and not requiring medication), simply postponing treatment until all symptoms have resolved is the most appropriate approach. 
    • While 6 weekly instillations are the optimal induction course for BCG, this is an arbitrary schedule that does not necessarily fit everyone. 
  • Consider dose reduction.
    • The recommended logarithmic reduction to 1/3, 1/10, 1/30 and 1/100th dose, for decades has shown that most symptoms can be managed with no observable reduction in efficacy. [6,7]
  • Consider prophylactic antibiotics.
    • Standard dose BCG plus ofloxacin 200 milligrams (mg) at 6 hours post instillation and the following morning has been demonstrated to have a significant reduction in local side effects with no reduction in efficacy. [8]
    • Isoniazid prophylaxis did not reduce the side effects of BCG in a large EORTC study. [9] 

How to treat moderate symptoms or BCG cystitis:

Moderate symptoms are often characterized by prolonged malaise, loss of appetite, night sweats and low grade fever which suggest a systemic infection. BCG cystitis is characterized by persistent severe frequency, urgency and dysuria, characteristic of BCG cystitis. The response to fluoroquinolones often occurs more promptly than the response to other types of antibiotics but should not be given for significant BCG infection as a single antibiotic.
  • A two-drug combination is generally sufficient for milder reactions treated early. 
    • Fluoroquinolone 
      • ofloxacin (200 to 400 mg every 12 hours)
      • ciprofloxacin (500 mg every 12 hours) 
      • levofloxacin (500 mg every 24 hours) 
    • Isoniazid 300 mg daily
  • For more intense or prolonged symptoms, a three drug combination is needed:
    • Rifampin 600 mg daily and/or 
    • Ethambutol 1200 mg daily 
      • Monthly eye examinations are recommended to optic neuritis (6%). [10]
  • Treatment is recommended for 3 to 6 months and symptoms may not even begin to improve for months after initiation of appropriate antibiotic therapy. 
  • Prednisone (30-60 mg daily, gradual taper) may be used in addition to antimicrobials if symptoms are unresponsive and intolerable.
  • Bladder contracture can occur is the rare circumstance that frequency and dysuria are not treated effectively.  

How to treat severe BCG-related symptoms and BCG-sepsis:

BCG sepsis is a rare complication (0.4%) [2] and is defined by high-fever and chills following BCG instillation.  The treatment of BCG sepsis includes:
  • Prompt hospital admission 
  • Broad-spectrum antibiotic coverage (triple antitubercular antibiotics)
Even with appropriate antibiotic treatment, hypotension followed by multisystem organ failure can occur. Due to an overwhelming immune response, steroid administration to suppress this immune hypersensitivity response (methylprednisolone 60-100 mg or more IV daily) can be life-saving. 

Patients with severe BCG reactions should not receive BCG in the future.Primates injected with one gram of BCG intravenously uniformly survive the infection, but a second intravenous injection in primates (like a second intraperitoneal BCG injection in rodents) is universally fatal.



How to treat patients who cannot tolerate BCG treatments:

Many patients would benefit from intravesical treatments but are unable to receive BCG due to side effects.  Options include dose-reduction and/or shortened course BCG treatments, radiation therapy,[11], heat-killed BCG [12] or other, novel BCG agents.  This will be the subject of a future blog.


Nilay M. Gandhi, MD

This entry was written by Nilay M. Gandhi, MD, senior assistant resident at the Brady Urological Institute at Johns Hopkins.  

Some of the data is extracted from the chapter Presentation and Management of Significant Side Effects from Bacillus Calmette-Guérin Bladder Instillation by Nilay M. Gandhi and Donald L. Lamm, which will appear in newest edition of The Textbook of Bladder Cancer.




[1] J.M. Molina, C. Rabian, M.F. D’Agay, J. Modai.  Hypersensitivity systemic reaction following intravesical bacillus Calmette-Guerin: successful treatment with steroids. J Urol, 147 (1992), p. 695
[2] D.L. Lamm, A.P.M. van der Meijden, A. Morales, S.A. Brosman, W.J. Catalona, H.W. Herr et al. Incidence and treatment of complications of bacillus Calmette-Guérin intravesical therapy in superficial bladder cancer.  J Urol, 147 (1992), p. 596
[3] P. Bassi, P. Nicola, R. Spinadin, R. Carando, F. Pagano, G.L. Papagallo. Low dose vs standard dose BCG therapy of superficial bladder cancer: final results of a phase 3 randomized trial. Eur Urol, 35 (1999), p. 152 suppl. abstract 
[4] J.A. Martínez-Piñeiro, J. Jiménez León, L. Martínez-Piñeiro Jr., L. Fiter, J.A. Mosteiro, J. Novarro et al.  Bacillus Calmette-Guerin versus doxorubicin versus thiotepa: a randomized prospective study in 202 patients with superficial bladder cancer. J Urol, 143 (1990), p. 502
[5] P.D. Vegt, A.P.M. van der Meijden, R. Sylvester, M. Brausi, W. Holtl, C. de Balincourt. Does isoniazid reduce side effects of intravesical bacillus Calmette-Guerin therapy in superficial bladder cancer? Interim results of the European Organization for Research and Treatment of Cancer protocol 30911. J Urol, 157 (1997), p. 1246
[6] J.A. Martinez-Pineiro, N. Flores, S. Isorna, E. Solsona, J.L. Sebastian, C. Pertusa et al.
Long-term follow-up of a randomized prospective trial comparing a standard 81 mg dose of intravesical bacilli Calmette-Guerin with a reduced dose of 27 mg in superficial bladder cancer
BJU Int, 89 (2002), p. 671
[7] P. Rivera, M. Orio, J. Hinostroza, P. Venegas, P. Pastor, M. Gorena et al.
Nuestra experiencia con instilaciones de 1 mg de vacuna BCG en cancer vesical etapa T1
Actas Urol Esp, 23 (1999), p. 757
[8] Colombel M, Saint F, Chopin D, Nicolas L, Rischmann P. The effect of ofloxacin on bacillus Calmette-Guérin induced toxicity in patients with superficial bladder cancer: Results of a randomized, prospective, double-blind, placebo controlled, multicenter study. J Urol 2006; 176: 935–9.
[9] Sylvester RJ, Brausi MA, Kirkels WJ, et al. Long-term efficacy results of EORTC genito-urinary group randomized phase 3 study 30911 comparing intravesical instillations of epirubicin, bacillus Calmette-Guérin, and bacillus Calmette-Guérin plus isoniazid in patients with intermediate- and high-risk stage Ta T1 urothelial carcinoma of the bladder. Eur Urol 2010; 57 (5): 766-73.
[10] Griffith DE, Brown-Elliott BA, Shepherd S, McLarty J, Griffith L, Wallace Jr, RJ. Ethambutol ocular toxicity in treatment regimens for Mycobacterium avium complex lung disease. Am J Respir Crit Care Med 2005; 172 (2): 250-3.
[11] Harland SJ, Kynaston H, Grigor K, Wallace DM, Beacock C, Kockelbergh R, Clawson S, Barlow T, Parmar MK, Griffiths GO. National Cancer Research Institute Bladder Clinical Studies Group: A randomized trial of radical radiotherapy for the management of pT1G3 NXM0 transitional cell carcinoma of the bladder. J Urol 2007; 178 (3): 807-13.
[12] Lamm DL, Gandhi NM, Iverson T, et al. Clinical experience with heat-inactivated bacillus Calmette-Guérin (BCG) immunotherapy. J Urol 2013; 4 (suppl): 733. 

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    1. HOW DR ALUALUA HELPED ME ENLARGE MY PENIS SIZE FROM 3.5 INCHES TO 11INCHES LONG AND 8.0 GIRTH
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    1. DR HARRY HERBAL CREAM HELPED ME TO ENLARGE MY PENIS SIZE FROM 3.5 INCHES TO 10 INCHES WITHIN TWO WEEKS OF TREATMENT

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  8. Very similar symptoms as you, almost died, organs failed 18 days in hospital. Recovering but still on the drugs for next 5 months. Symptoms started at 5th treatment.

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  9. hello everyone in this forum i am little bit ashamed to share this marvelous story about a great spell caster who helped me enlarge my small penis size through his herbal mixture cream,i was heartbroken before because i have a very small penis about 3 inches which was so annoying and shameful i could not satisfy my wife in bed ,,my marriage was really breaking and i needed help urgently,i have used pills,vaccines,drugs,surgery but none worked...so one faithful day as i was browsing through the internet i saw few comments on a forum about how Mr MARK HENRY from UK testified of how he helped him enlarge his penis and also cured his MOM diabetes type 2 disease,,i contacted him through his email enlargementherbs@yahoo.com he replied and gave me steps to follow and i did just as he said ,and he sent me the herbal cream to me through UPS and i received it within 4 days and used the herbal cream for just 14 days to my greatest surprise my penis that was 3 inches before enlarge to 10.5 inches long when fully erected ,for just two weeks of using his herbal mixture cream ,,wow my wife loved me more and was so happy that i can satisfy her very well now in bed ,,i even last longer than before thank you so much DR James for making life a better one to live in ..so if you are out there having similar problems please contact him now on his email enlargementherbs@yahoo.com or whatsapp and call him on +2349055637784 thanks

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  11. hello everyone i am Anthony walters from USA i never thought i will be happy in my life again because of my small penis situation,i have struggling with this issue my life time and i could not find a professional result i wanted ,i ave went to hospitals,used vaccines,tried several herbs online ,penis pumps and all but none rendered me the solution i wanted ,i felt like killing myself when my fiance JENNIFER the woman i wanted to get married to in 1month time left me after undressing myself in front of her,my size was too embarrassing and shameful imagine a 37years old man like having 3.0inches penis size..the world seem to an end to me when we she left so one faithful day as i was watching a video on youtube i saw the comments of one MR MARIO MAMARU ABIYE testifying of this great herbal healer DR HARRY helped him enlarge his penis .i was shocked and happy so i quickly visited his website https://drharrysolution7.wixsite.com/solutiontemple and emailed him within 30mins he got back to me and told me all i need to buy and i did so after 4 days i received his herbal medicine ,he gave me instructions on how to use it ,as i am speaking to you people now after using the cream for just two weeks my penis size is 10 inches long and 8.0 girth ,,am so happy and grateful for his work in my life thank you so much dr harry ,,i later got married last week and i am a happy man now i also learnt he has cure for LOW SPERM COUNT,PREMATURE EJACULATION,ERECTILE DYSFUNCTION,HIV/AIDS VIRUS,DIABETES 1/2,HERPES DISEASE,PROSTRATE CANCER,ALS,HPV,LOVE SPELL and lots more you can email him on drharrysolution@gmail.com or call/whatsapp him directly on +2348143240563 you can text or call me on my number +14086506534 thanks

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  16. Hello everyone. I was heartbroken because i had very small penis, not nice to satisfy a woman, i had so many relationship called off because of my situation, i have used so many product which i found online but none could offer me the help i searched for. i saw some few comments about this doctor called Dr. OMOHAN and I decided to email him on: dromohanherbalmedicine@gmail.com so I decided to give his herbal product a try. i emailed him and he got back to me, he gave me some comforting words with his herbal cream for Penis Enlargement, Within 1 week of it, i began to feel the enlargement of my penis, " and now it just 2 weeks of using his products my penis is about 9 inches longer and strong. I'm so happy..feel free to contact DR OMOHAN on his Email: dromohanherbalmedicine@gmail.com or you can also call him on the whatsapp contact +2348164816038

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  17. HOW DR OSUMEN HELPED ME ENLARGE MY PENIS SIZE FROM 3.5 INCHES TO 11INCHES LONG AND 8.0 GIRTH
    hello everyone this is serious and real i want to tell the whole world about how DR OSUMEN HERBAL MIXTURE CREAM helped me enlarge my penis size ..i have trying since 19 years of age to enlarge my penis but none rendered me the help i want i have used vaccines,penis pump,surgery,online creams from USA SAMOA,CANADA CAMBODIA,AUSTRALIA and many more but none of them enlarge my penis i was really frustrated and tired of living because my penis was too small ,imagine a cute and handsome 36years old man like me having 3.5 inches and to make it worse i was having erectile dysfunction which was so annoying to me,my girlfriends have left me because of my small penis ....to GOD be the glory as i was searching for help on a facebook page i saw one mr JEREMY WILLIAMS from italy testifying of how DR OSUMEN MIXTURE CREAM enlarge his penis and healed his grandmom PROSTRATE CANCER .so i quickly visited his website link and message him on his email i saw on the website and he replied me and gave me comforting words and told me all i need to do and i was surprise he did not ask for money ,,i got his cream and he sent it to me through united parcel service (UPS)and i got it 4 days later and used the cream just as he told me and its just 1 days of using his herbal mixture my penis is now 11 inches long and 8.0 flaccidity am so happy to feel like a man in the bedroom at last so if you need penis enlargement,DIABETES 1/2 CURE,HERPES CURE,HIV/AIDS,CANCER,ALOPECIA,LUPUS DISEASE,PILE,LOW SPERM COUNT,PREMATURE EJACULATION,ERECTILE DYSFUNCTION,breast enlargement,weak erection,erectile dysfunction cure and many sexual relation cure do not hesitate to email him now drosumensolutiontemple@gmail.com or you can also call him on+2349038505515 +2348105275315.

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  18. My names are HARRY MARY I’m a citizen of United Kingdom, My younger sister was sicking of breast cancer and her name is HARRY Sandra I and my family have taking her to all kind of hospital in UK still yet no good result. I decided to go to the internet and search for cancer cure so that was how I find a lady called peter Lizzy she was testifies to the world about the goodness of a herbal man who has the root and half to cure all kind of disease and the herbal man email was there. So I decided to contact the herbal man for my younger sister help to cure her breast cancer. I contacted him and told him my problem he told me that I should not worry that my sister cancer will be cure, he told me that there is a medicine that he is going to give me that I will cook it and give it to my sister to drink for one week, so I ask how can I receive the cure that I am in UK, he told me

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    Replies
    1. HOW DR ODUMU HELPED ME ENLARGE MY PENIS SIZE FROM 3.5 INCHES TO 11INCHES LONG AND 8.0 GIRTH
      hello everyone this is serious and real i want to tell the whole world about how DR ODUMU HERBAL MIXTURE CREAM helped me enlarge my penis size ..i have trying since 19 years of age to enlarge my penis but none rendered me the help i want i have used vaccines,penis pump,surgery,online creams from USA SAMOA,CANADA CAMBODIA,AUSTRALIA and many more but none of them enlarge my penis i was really frustrated and tired of living because my penis was too small ,imagine a cute and handsome 36years old man like me having 3.5 inches and to make it worse i was having erectile dysfunction which was so annoying to me,my girlfriends have left me because of my small penis ….to GOD be the glory as i was searching for help on a facebook page i saw one MR JEREMY WILLIAMS from italy testifying of how DR ODUMU MIXTURE CREAM enlarge his penis and healed his grandmom PROSTRATE CANCER .so i quickly visited his website link and message him on his email i saw on the website and he replied me and gave me comforting words and told me all i need to do and i was surprise he did not ask for money ,,i got his cream and he sent it to me through united parcel service (UPS)and i got it 4 days later and used the cream just as he told me and its just 1 days of using his herbal mixture my penis is now 11 inches long and 8.0 flaccidity am so happy to feel like a man in the bedroom at last so if you need penis enlargement,DIABETES 1/2 CURE,HERPES CURE,HIV/AIDS,CANCER,ALOPECIA,LUPUS DISEASE,PILE,LOW SPERM COUNT,PREMATURE EJACULATION,ERECTILE DYSFUNCTION,breast enlargement,weak erection,erectile dysfunction cure and many sexual relation cure do not hesitate to email him now drodumusolutiontemple@gmail.com or you can also call him on+2348147048549 thanks

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  19. Hello from united kingdom...i have been having sexual battles with my wife in my marriage because of my small penis and it was really so embarrassing imagine a grown up man of 39 years old having a small dick...i could not satisfy her and she threatened to cheat on me if i do not find a way..i searched for cure and results but none of them avail..i even used online pills,vaccines,drugs,herbal herbs but still no result so i was about going penis Suggerry when i read about this great herbalist called him odiagbe ..i quickly message him and he got back to me within 30 mins and told me all i need to do ,,i followed all his instructions and he sent down his herbal cream through UPS SERVICE to me and gave me instruction on how to apply it and within two weeks i was Beginning to feel myself ...i now measure 10.5 inches long in erection and 8.0 girth fat ...my wife is so proud and happy with me now..All thanks to DR ODIAGBE for saving my marriage ..i am 100% grateful to you sir .NOTE he also have herbal remedies to problems like
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  20. Hello viewers around the Globe, I was despondent because i had a very small penis, about 2.5 inches soft and 4 inches hard not nice enough to satisfy a woman, i have been in so many relationship, but cut off because of my situation, i have used so many product which doctors prescribe for me, but none could offer me the help i searched for. i saw some few comments on the INTERNET about this specialist called Dr,ODIAGBE and decided to contact him on his email: [drodiagbeherbalhome1@gmail.com] so I decided to give his herbal product a try. i emailed him and he got back to me, he gave me some comforting words with his herbal pills for Penis Enlargement, Within 3 week of it, i began to feel the enlargement of my penis, " and now it just 4 weeks of using his products my penis is about 9 inches longer, and i had to settle out with my Ex girlfriend JOY, i was surprised when she said that she is satisfied with my sex and i have got a large penis. Am so happy, thanks to Dr ODIAGBE I also learn that Dr ODIAGBE also help with Breast Enlargement Hips and Bums Enlargement etc.. If you are in any situation with a little Penis, weak ejaculation, small breast_hips_bums do get to Dr ODIAGBE now for help on his email [drodiagbeherbalhome1@gmail.com]

    ReplyDelete
  21. god bless who is reading this testimony, I am happy for given the opportunity to share my experience about Dr. odiagbe who is a great and specialized herbal doctor who only treats with the used of powerful herbs. My fiancee always do complained every time when we are having sex and sometimes after sex, all just because I was having a small Dick and it does not satisfy her the way she wants it. Sometimes, i get weak during sex to the extent I can't even go for just two rounds, I myself was not happy about it and even before I met her others girls do complain and some even do cheat on me because I am having a small dick. But for this my present girlfriend, I love her so much and I want to marry her, I just can't stay and open my eyes letting other guys out there taking her from me or seeing her cheating on me, I undergo several medical treatment which did not work out and even eat up lot of my money. One blessed and faithful morning, I was talking to a friend of mine and I seek helped from him on how to get my dick more enlarge so that I can satisfy every woman in my life because I knew he was having a huge dick and because of that many girls do ran after him. He make mentioned of Doctor amos and told me never to share the secrete out, I said ok, and he told me everything how he got a big dick just within one week of using the medicine only, it was surprising though and he contacted the doctor in my present and said to him a friend wants to speak with him, he gave me the phone I explained everything to doctor and the doctor said I should send him my home address and full names and promised me that once I started taking it I will start seeing changes after three days because its very powerful and I am not allowed to have sex not until I completed taking the meds for one week. After two days I received the medicine and I used according to the instructions instantly after three days I started seeing changes, and one of the changes was my dick do get up and stand for like ten minutes before going down. When I finished taking the medicine, I called him and inform him and he said I should have sex now and tell him the outcome after sex, which I did in the mid night with my fiancee, she screamed so hard and tell me to fuck her so hard now she is enjoying me the more, throughout good three to four hours I was still having sex and before I cumed, she suck me so hard and the biggest joy about it was my dick was no longer small but was now long and so thick. I called the doctor the next morning and tells him the good news and I promised him that I will tell more people about him so that's why I am here sharing this great testimony of mine because I am a living witness and I am so excited about it because it has no effect on me, right now, I am the one even running from sex because she keeps disturbing me every time she wants more and more. Contact doctor today if you are having any issues on his email address drodiagbeherbalhome1@gmail.com or add him on whatsapp +2348103553159
    Once again all thanks to great Dr Odiagbe

    ReplyDelete
  22. Hello from united kingdom...i have been having sexual battles with my wife in my marriage because of my small penis and it was really so embarrassing imagine a grown up man of 39 years old having a small dick...i could not satisfy her and she threatened to cheat on me if i do not find a way..i searched for cure and results but none of them avail..i even used online pills,vaccines,drugs,herbal herbs but still no result so i was about going penis Suggerry when i read about this great herbalist called him odiagbe ..i quickly message him and he got back to me within 30 mins and told me all i need to do ,,i followed all his instructions and he sent down his herbal cream through UPS SERVICE to me and gave me instruction on how to apply it and within two weeks i was Beginning to feel myself ...i now measure 10.5 inches long in erection and 8.0 girth fat ...my wife is so proud and happy with me now..All thanks to DR ODIAGBE for saving my marriage ..i am 100% grateful to you sir .NOTE he also have herbal remedies to problems like
    1.LOW SPERM COUNT
    2.PREMATURE EJACULATION
    3.ERECTILE DYSFUNCTION
    4.DIABETES CURE
    5.HIV/AIDS CURE
    6.CANCER CURE
    7.GENITAL HERPES CURE
    8.STROKE
    9.HEART FAILURE
    so if you are out there and need such help please contact him on
    drodiagbeherbalhome1@gmail.com still drodiagbeherbalhome1@gmail.com

    ReplyDelete
  23. WHAT A GREAT MIRACLE THAT I HAVE EVER SEE IN MY LIFE. My names are David
    Clara I’m a citizen of United Kingdom, My younger sister was sicking of
    breast cancer and her name is David Sandra I and my family have taking her
    to all kind of hospital in UK still yet no good result. I decided to go to
    the internet and search for cancer cure so that was how I find a lady
    called peter Lizzy she was testifies to the world about the goodness of a
    herbal man who has the root and half to cure all kind of disease and the
    herbal man email was there. So I decided to contact the herbal man for my
    younger sister help to cure her breast cancer. I contacted him and told him
    my problem he told me that I should not worry that my sister cancer will be
    cure, he told me that there is a medicine that he is going to give me that
    I will cook it and give it to my sister to drink for one week, so I ask how
    can I receive the cure that I am in UK, he told me

    That I will pay for the delivery service. The courier service can
    transport it to me so he told me the amount I will pay, so my dad paid for
    the delivery fee. two days later I receive the cure from the courier
    service so I used it as the herbal man instructed me to, before the week
    complete my sister cancer was healed and it was like a dream to me not
    knowing that it was physical I and my family were very happy about the
    miracle of Doctor so my dad wanted to pay him 5 million us dollars the
    herbal man did not accept the offer from my dad, but I don't know why he
    didn't accept the offer, he only say that I should tell the world about him
    and his miracle he perform so am now here to tell the world about him if
    you or your relative is having any kind of disease that you can't get from
    the hospital please contact dr.sakuraspellalter@gmail.com or whatsapp him
    +2348110114739 <+234%20811%20011%204739> for the cure, he will help you
    out with the
    problem. And if you need more information about the doctor you can mail me
    davidclara223@gmail.com or whatsApp me +1(6)31906022

    ReplyDelete
  24. Hello viewers around the Globe, I was despondent because i had a very small penis, about 2.5 inches soft and 4 inches hard not nice enough to satisfy a woman, i have been in so many relationship, but cut off because of my situation, i have used so many product which doctors prescribe for me, but none could offer me the help i searched for. i saw some few comments on the INTERNET about this specialist called Dr,MOSES BUBA and decided to contact him on his email: buba.herbalmiraclemedicine@gmail.com) so I decided to give his herbal product a try. i emailed him and he got back to me, he gave me some comforting words with his herbal pills for Penis Enlargement, Within 3 week of it, i began to feel the enlargement of my penis, " and now it just 4 weeks of using his products my penis is about 9 inches longer, and i had to settle out with my Ex girlfriend JOY, i was surprised when she said that she is satisfied with my sex and i have got a large penis. Am so happy, thanks to Dr MOSES BUBA I also learn that Dr MOSES BUBA also help with Breast Enlargement Hips and Bums Enlargement etc.. If you are in any situation with a little Penis, weak ejaculation, small breast_hips_bums do get to Dr MOSES BUBA now for help on his email ( buba.herbalmiraclemedicine@gmail.com ).

    .....

    ReplyDelete
  25. Hello everyone. I was heartbroken because i had very small penis, not nice to satisfy a woman, i had so many relationship called off because of my situation, i have used so many product which i found online but none could offer me the help i searched for. i saw some few comments about this doctor called Dr. AMOS and I decided to email him on: Dramosehikioyaspelltemple@gmail.com so I decided to give his herbal product a try. i emailed him and he got back to me, he gave me some comforting words with his herbal cream for Penis Enlargement, Within 1 week of it, i began to feel the enlargement of my penis, " and now it just 2 weeks of using his products my penis is about 9 inches longer and strong. I'm so happy..feel free to contact DR AOS on his Email: Dramosehikioyaspelltemple@gmail.com or you can also call him on the whatsapp contact +2348103553159

    ReplyDelete
  26. Hello everyone. I was heartbroken because i had very small penis, not nice to satisfy a woman, i had so many relationship called off because of my situation, i have used so many product which i found online but none could offer me the help i searched for. i saw some few comments about this doctor called Dr. AMOS and I decided to email him on: Dramosehikioyaspelltemple@gmail.com so I decided to give his herbal product a try. i emailed him and he got back to me, he gave me some comforting words with his herbal cream for Penis Enlargement, Within 1 week of it, i began to feel the enlargement of my penis, " and now it just 2 weeks of using his products my penis is about 9 inches longer and strong. I'm so happy..feel free to contact DR AOS on his Email: Dramosehikioyaspelltemple@gmail.com or you can also call him on the whatsapp contact +2348103553159

    ReplyDelete
  27. I was cured of HIV with the used of natural herbs. My name is celina jolly and am from US. I love herbs so much. Most times, injection and drugs are just a waste of time. I was cured 8 months ago, i suffered from HIV for 13 yrs but with the help of Dr.Ogun herbal medicine, i was cured within few weeks of drinking the herbs he sent to me through courier delivery service. This same doctor also cured my Aunty from herpes, as soon as i heard she had herpes, i quickly refer her to Dr.Ogun and she was cured too after drinking his herbs.I have referred more than 15 persons to Dr.Ogun and they were all cured from their various illness. Have you taken herbs before?. You have spent so much money on drugs,injections,surgeries etc and yet you have no good result to show for it. Contact Dr. Ogun now, he is a herbalist doctor, i assured you of a cure if you drink his natural herbs. Dr.Ogun have herbs that cures Hiv, Herpes, diabetics, asthma, hepatitis, HBP, STD, cancer, chronic, etc. Contact Dr ogun through his Email address on: drogun62@gmail.com or WHATSAPP/CALL him on+2348104991149 . Please share the good news to other people once you are cured

    ReplyDelete
  28. I was cured of HIV with the used of natural herbs. My name is celina jolly and am from US. I love herbs so much. Most times, injection and drugs are just a waste of time. I was cured 8 months ago, i suffered from HIV for 13 yrs but with the help of Dr.Ogun herbal medicine, i was cured within few weeks of drinking the herbs he sent to me through courier delivery service. This same doctor also cured my Aunty from herpes, as soon as i heard she had herpes, i quickly refer her to Dr.Ogun and she was cured too after drinking his herbs.I have referred more than 15 persons to Dr.Ogun and they were all cured from their various illness. Have you taken herbs before?. You have spent so much money on drugs,injections,surgeries etc and yet you have no good result to show for it. Contact Dr. Ogun now, he is a herbalist doctor, i assured you of a cure if you drink his natural herbs. Dr.Ogun have herbs that cures Hiv, Herpes, diabetics, asthma, hepatitis, HBP, STD, cancer, chronic, etc. Contact Dr ogun through his Email address on: drogun62@gmail.com or WHATSAPP/CALL him on+2348104991149 . Please share the good news to other people once you are cured

    ReplyDelete
  29. Hello everyone, am very happy to share this little awesome testimony about Dr kobeko enlargement home for the good help and his herbal cream, my penis size was small and I worried about my marriage, I consulted number of doctors but there is no solution for my problem, i took Viagra and others but stopped when my doctor advised against it. But recently a friend told about Dr kobeko penis enlargement skills, i thought it through and gave a try to see if it would help and just in few weeks my penis is already in good length, those who are looking for penis enlargement shouldn't waste so much amount spending on surgeries, contact Dr kobeko guide for natural solution on Pines Enlargement.


    WHATSAPP NUMBER :+2347050579374
    EMAIL : drkobekoenlargementhome@gmail.com

    ReplyDelete
  30. Hello everyone i Am williams pster and i am from USA i am here to give my testimony about an herbal doctor called Dr,Olu I was heartbroken because i had very small penis,not nice to satisfy a woman, i have been in so many relationship, but cut off because of my situation, i have used so many product which doctors prescribe for me, but could not offer me the help i searched for. i saw some few comments on the internet about this specialist called Dr,Olu and decided to email him on his email i saw on the internet,(drolusolutionhome@gmail.com ) so I decided to give his herbal product a try. i emailed him and he got back to me, he gave me some comforting words with his herbal product for Penis Enlargement, Within three weeks of me use it, i began to feel the enlargement, " and now it just 4 weeks of using his products my penis is about 8 inches longer, and i had to settle thing out with my ex girlfriend , i was surprised when she said that she is satisfied with my performance in bed and i now have a large penis.thanks to DR Olu for is herbal product. you can also reach him with emsil drolusolutionhome@gmail.com though is..number WHATASPP him today on this number [ +2348140654426

    ReplyDelete
  31. Dr. Sam has really made me so much believe in him by getting me cured with his herbal treatment. i really appreciate you Dr.Sam for bringing back happiness to my life again. thanks you so much,friends join me to thank him for what he has actually done for me i pray to you all for a good life and good health, and most especially to you Dr. Sam THANKS.

    I have been suffering from (HERPES SIMPLEX VIRUS) disease for the past four years and had constant pain, especially in my knees. During the first year,I had faith in God that i would be healed someday.This disease started circulating all over my body and i have been taking treatment from my doctor, few months ago i came on search on the internet if i could get any information concerning the cure of this disease, on my search i saw a testimony of someone who has been healed from (HERPES SIMPLEX VIRUS) by this Man Dr Sam and she drop the email address of this man and advise we should contact him for any sickness that he would be of help, so i wrote to Dr. Sam telling him about my (HERPES Virus) well after all the procedures and remedy given to me by this man few weeks later i started experiencing changes all over me. I am now here to testify that i am not longer a herpes patient, I have experience a total transformation in my life,for all herpes patients get your herbal medicine to cure your sickness. And there has being rapid improvement in my health, I no longer feel pains and I wake up each morning feeling revived. So friends my advise is if you have such sickness or any other at all,you can contact him. (Supremecurehome@gmail.com) Wbesite: http://www.supremecurehome.blogspot.com
    CANCER
    EPILEPSY.
    GENPILENCIN.
    HIV AIDS.
    DIABETICS
    STROKE.
    EXPANDS OF PENIS BREAST
    H.P.V TYPE 1 TYPE 2 TYPE 3 AND TYPE 4. TYPE 5.
    HUMAN PAPAILOMA VIRUS.
    HERPES.
    SYPHILIS.
    HEPATITIS A B and C.

    Email: Supremecurehome@gmail.com WhatsApp number +2347087462033

    ReplyDelete
  32. DR HARRY HERBAL CREAM HELPED ME TO ENLARGE MY PENIS SIZE FROM 3.5 INCHES TO 10 INCHES WITHIN TWO WEEKS OF TREATMENT

    hello everyone in this forum my name is monty williams i am a bit ashamed to share this story about a great DOCTOR called DR HARRY who helped me enlarge my small penis size through his herbal mixture cream,i was heartbroken before because i have a very small penis about 3.5 inches which was so annoying and shameful i could not satisfy my wife in bed ,,my marriage was really breaking and i needed help urgently,i have used pills,vaccines,drugs,surgery but none worked...so one faithful day as i was browsing through the internet i saw few comments on a forum about DR HARRY and how He helped Mr MARK from UK to enlarge his penis and also cured his MOM diabetes type 2 disease,,i contacted him through his email drharrysolution@gmail.com he replied and gave me steps to follow and i did just as he said ,and he sent me the herbal cream to me through UPS and i received it within 4 days and i used the herbal cream for just 14 days to my greatest surprise my penis that was 3.5 inches before enlarge to 10 inches long when fully erected ,for just two weeks of using his herbal mixture cream ,,wow my wife loved me more and was so happy that i can satisfy her very well now in bed ,,i even last longer than 2hours in bed. the medical confirmed my wife one week pregnant thank you so much DR HARRY for making life a better one to live in ..so if you are out there having similar problems please contact him now on his email drharrysolution@gmail.com
    website https://drharryherbaltempl.wixsite.com/solutiontemple or whatsapp and call him on +2349036417079 thanks

    ReplyDelete
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    ReplyDelete

  34. Am here to appreciate Dr.Zack Balo for using his herbal medicine to cure my Herpes virus. since 2016 now I have been living with this virus and it has been giving me challenges, I was so perplexed cause i have been taking several drugs to be cured but all of my effort was in vain,one evening i was browsing through the internet then i saw several testimonies about Dr.Zack Balo curing people from Herpes virus and immediately i contacted Dr.Zack Balo on his email address: wiseindividualspell@gmail.com, i told him about my sickness and he told me that i will be cured within 14 days, gave me some instructions and which i rightly followed. so he prepared a herbal medicine for me and sent it to me which i used for 2 weeks and everything was like a dream to me and my Herpes virus was totally gone, why don't you contact him today and be free from your diseases because he is very good and honest Doctor. contact him via email address;wiseindividualspell@gmail.com or call or text him on his phone number +13203967742.

    ReplyDelete

  35. Am here to appreciate Dr.Zack Balo for using his herbal medicine to cure my Herpes virus. since 2016 now I have been living with this virus and it has been giving me challenges, I was so perplexed cause i have been taking several drugs to be cured but all of my effort was in vain,one evening i was browsing through the internet then i saw several testimonies about Dr.Zack Balo curing people from Herpes virus and immediately i contacted Dr.Zack Balo on his email address: wiseindividualspell@gmail.com, i told him about my sickness and he told me that i will be cured within 14 days, gave me some instructions and which i rightly followed. so he prepared a herbal medicine for me and sent it to me which i used for 2 weeks and everything was like a dream to me and my Herpes virus was totally gone, why don't you contact him today and be free from your diseases because he is very good and honest Doctor. contact him via email address;wiseindividualspell@gmail.com or call or text him on his phone number +13203967742.

    ReplyDelete
  36. Greetings to the general public, i want to inform the public how i was cured of HERPES Simplex Virus by a man called Dr Azuka. i visited different hospital but they gave me list of drugs like Famvir, Zovirax, and Valtrex which is very expensive to treat the symptoms and never cured me. I was browsing through the Internet searching for remedy on HERPES and i saw comment of people talking about how Dr Azuka cured them. I was scared because i never believed in the Internet but i was convince to give him a try because i was having no hope of been cured of HERPES so i decided to contact him on his email that was listed on the comment ( Dr.azukasolutionhome@gmail.com ) i searched his email on net and i saw a lot of people testifying about his goodness. when i contacted him he gave me hope and send a Herbal medicine to me that i took and it seriously worked for me, am a free person now without problem, my HERPES result came out negative. I pray for you Dr Azuka God will give you everlasting life, you shall not die before your time for being a sincere and great man. Am so happy, you can also contact him if you have any problem Email : DR.AZUKASOLUTIONHOME@GMAIL.COM

    DR AZUKA CAN AS WELL CURE THE FOLLOWING DISEASE:-

    HSV 1 & HSV 2
    ASTHMA
    DIABETES
    EPILEPSY
    CANCER
    INFERTILITY
    STAPHYLOCOCCUS.
    BARENESS
    HEPATITIS B
    PENIS ENLARGEMENT
    ALS

    ReplyDelete
  37. Hello viewers around the Globe, I was despondent because i had a very small penis, about 2.5 inches soft and 4 inches hard not nice enough to satisfy a woman, i have been in so many relationship, but cut off because of my situation, i have used so many product which doctors prescribe for me, but none could offer me the help i searched for. i saw some few comments on the internet about this specialist called Dr, OMOHAN and i decided to contact him on his EMAIL i saw on the internethttp:/{dromohanherbalmedicine@gmail.com} so I decided to give his herbal product a try. i emailed him and he got back to me, he gave me some comforting words with his herbal pills for Penis Enlargement, Within 3 week of it, i began to feel the enlargement of my penis, " and now it just 4 weeks of using his products my penis is about 9 inches longer, and i had to settle out with my Ex girlfriend Ella, i was surprised when she said that she is satisfied with my sex and i have got a large penis. Am so happy, thanks to Dr OMOHAN I also learn that Dr OMOHAN also help with Breast Enlargement Hips and Bums Enlargement etc.. If you are in any situation with a little Penis, weak ejaculation, small breast_hips_bums do get to Dr OMOHAN now for help on his email {dromohanherbalmedicine@gmail.com} or whats app him number: +2348164816038}

    ReplyDelete
  38. i am from Texas US. I want to share a testimony
    of how Dr. odudu herbal mixture cream saves me from shame and
    disgrace, my penis was a big problem to me as the size was really so
    embarrassing,and i was also having weak erection problem. I can make
    love to my wife and my penis was just too small a full grown man like
    me having 4 inches penis and to worsen it i don't last in sex i cant
    even last two minutes it was really a thing of shame to me. My wife
    was really tired of me because my sex life was very poor,she never
    enjoyed sex,i was always thinking and searching for solutions
    everywhere until when i saw a testimony of how Dr. odudu herbal
    mixture cream have been helping people regarding their sex life, so i
    decided to give him a try and to my greatest surprise in less than one
    week of taking the herbs my penis grow to 8 inches i couldn't believe
    my eyes and as i speak now my penis is now 8 inches and i do not have
    week erection again. I can make love to my wife longer in bed. And my
    marriage is now stable,my wife now enjoy me very well in bed. You can
    contact him via dr.oduduherbalhome@gmail.com https://web.facebook.com/DR.ODUDUHERBALHOME/?fref=ts
    you can also call and whatsapp him on via no
    +2348101571054 Thanks for curing my weak erection and for the Enlarge penis you did to me to save my
    marriage...I am really grateful sir,

    ReplyDelete
  39. hello everyone this is real and i want to tell the whole world about
    how DR OSCAR HERBAL CREAM and LIQUID helped me enlarge my penis size,
    i have been trying since 23 years of age to enlarge my penis but none rendered
    me the help i want i have used vaccine ,penis pump,surgery,online creams
    from USA SAMOA,CANADA CAMBODIA and more but none of them enlarge my penis
    i was really frustrated and tired of living because my penis was too small
    ,imagine a cute and handsome man of 38 years old like me having 3.5 inches
    and to make it worse i was having erectile dysfunction which was so annoying
    to me,my girlfriends have left me because of my small penis ....to GOD be the
    glory as i was searching through the online for help on a facebook page i saw
    one Mr john from USA testifying of how DR OSCAR HERBAL CREAM and LIQUID enlarge
    his penis from 3 inches to 10 inches within two weeks of using his herbal cream..
    so i quickly contacted him through his email droscarenlargementhome@yahoo.com and
    message him and he replied me and gave me comforting words and He told me all i
    need to do and i was surprise after one week of using his cream my penis enlarge to
    7 inches and is now 10 inches long and very thicker i am so happy to feel like a real
    man in the bedroom at last so if you need penis enlargement,breast enlargement,weak
    erection,erectile dysfunction cure and many sexual relation cure do not hesitate to
    email him now on droscarenlargementhome@yahoo.com

    ReplyDelete
  40. Am Gladys by name, i was diagnosed with Herpes for 6 years ago i lived in pain with the knowledge that i wasn't going to ever be well again i contacted so many herbal doctors on this issue and wasted a large sum of money but my condition never got better i was determined to get my life back so one day i saw mr Brown post on how Dr Iyoha saved him from the VIRUS with his herbal medicine i contacted Dr Iyoha on his email address driyohasolutiontemple@yahoo.com we spoke on the issue i told him all that i went through and he told me not to worry that everything will be fine again so he prepared the medicine and send it to me through courier service and told me how to use it,after 14 days of usage I went to see the doctor for test ,then the result was negative,am the happiest woman on earth now. this testimony is real.thanks to Dr Iyoha God bless you. you can also reach him on his number +1 (407) 337-9869

    ReplyDelete
  41. hello everyone i am from USA penis enlargement and erectile dysfunction has been a problem to me for more than 5 years,my wife always get disappointed with me when ever we have sex in bed,i don’t last for up to three minute,during sex, i have taking different medication but to no solution,then i went on the net for a solution on how to enlarge my penis and i got DR SALATO who help in cure erection and ejaculation problem with his product and also help to enlarge penis,i got in touch with him through is email drsalatosolutiontemple@gmail.com or website http://drsalatosolutionte0.wixsite.com/drsalato ,he replied me and gave me steps to follow and i got his herbal product. which i took for just 2 weeks and my premature ejaculation is now normal and my erection is hard and my
    penis got bigger up to 10 inches and 6.5 girth than before and now i can last long in bed. now 10.5 inches long on erection and off course very large round. I am very happy for this Penis Enlargement experience no side effect . He can help with all kinds of cure or spell you may need as follows
    get ex lover or husband back spell :
    money and promotion spell
    employment spell
    marry me spell
    seduction spell
    lottery or lotto spell
    protection spell
    win election or court case spell
    Penis Enlargement
    Low sperm count
    Weak Erection
    long time sickness
    kidney,heart,lungs,problem
    with DR SALATO you are in safe hands your healing is assured
    Email:drsalatosolutiontemple@gmail.com or
    website http://drsalatosolutionte0.wixsite.com/drsalato.. you can for whatsapp number: +2348103629945 thanks

    ReplyDelete
  42. Hello everyone, my name is ALFREED SIANG i am here to say a big thank you to my doctor DR OLU who helped me enlarge my penis.i have never had a happy relationship in my life because of my inability to perform well due to my small penis, due to frustration,i went online in search of solution to ending my predicament and than i came across testimony on how DR OLU has helped them, so i contacted him and he promised to help me with penis enlargement,i doubted at first but i gave him a trial and he sent me the product which i used according to his prescription and in less than a week,i saw changes in my penis and it grow to the size i wanted and since then,i am now a happy man and no lady complains again about my penis.if you also need the services of my doctor,you can also contact him on his email..drolusolutionhome@gmail.com


    ReplyDelete
  43. What do you think about this recipe?My name is john terry,i just want to
    share my testimony with the world on how Doctor udo Help me to enlarge my
    penise. Please read my good news carefully and i am sure it will affect your
    life positively on how you will also enlarge your pines,because i know some
    many people out there also need his help! I came across so many comments
    about Dr udo Penis Enlargement Medicine some weeks ago, though I had
    really wanted my penis to be large, long and thick,because i was not able
    to have sex with my wife..It was really affecting our marriage and my wife
    was about to divorce me. I had about 3.7cm – 3.2 inches before. Am really
    amazed on the fast results archived within 14 days of using Dr udo Penis
    Enlargement Medicine. It work and now I have got 22.87cm – 10.5 inches now.
    And my wife love it more now, i began to feel the enlargement of my penis,
    This went on for a little period of about 5 days and to my surprise my wife
    keeps screaming that she love my big dick now. And my penis is now 10.5
    inches long on erection and off course very large round. I am very happy
    for this Penis Enlargement experience. Email him udosolutiontemple@gmail.com
    now
    Whatsapp or call +2348151972510 PENIS Enlargement,
    Low sperm count,
    Weak
    Erection,
    Love spell,
    Herpes cure,
    HIV cure,
    watering sperm,
    penise
    erection,
    s.t.d diseases,
    internal heat rashes,
    low sperm count,
    dairy long
    time
    sickness kidney, your problem with doctor,Dr udo you are in safe hands your healing is awesome Email>udosolutiontemple@gmail.com or whatsapp
    +2348151972510
    or SMS.

    ReplyDelete
  44. What do you think about this recipe?My name terry, i just want to
    share my testimony with the world on how Doctor udo Help me to enlarge my
    penise. Please read my good news carefully and i am sure it will affect your
    life positively on how you will also enlarge your pines,because i know some
    many people out there also need his help! I came across so many comments
    about Dr udo Penis Enlargement Medicine some weeks ago, though I had
    really wanted my penis to be large, long and thick,because i was not able
    to have sex with my wife..It was really affecting our marriage and my wife
    was about to divorce me. I had about 3.7cm – 3.2 inches before. Am really
    amazed on the fast results archived within 14 days of using Dr udo Penis
    Enlargement Medicine. It work and now I have got 22.87cm – 10.5 inches now.
    And my wife love it more now, i began to feel the enlargement of my penis,
    This went on for a little period of about 5 days and to my surprise my wife
    keeps screaming that she love my big dick now. And my penis is now 10.5
    inches long on erection and off course very large round. I am very happy
    for this Penis Enlargement experience. Email him udosolutiontemple@gmail.com
    now
    Whatsapp or call +2348151972510 PENIS Enlargement,
    Low sperm count,
    Weak
    Erection,
    Love spell,
    Herpes cure,
    HIV cure,
    watering sperm,
    penise
    erection,
    s.t.d diseases,
    internal heat rashes,
    low sperm count,
    dairy long
    time
    sickness kidney, your problem with doctor,Dr udo you are in safe hands your healing is awesome Email>udosolutiontemple@gmail.com or whatsapp
    +2348151972510
    or SMS.

    ReplyDelete
  45. I am Williams, I have read a lot of Dr Mabuwa breakthrough Testimonies and that's what inspired me to contact this great herbal Man, i am a sufferer of Hepatitis B this was such a disastrous disease that almost took my life somethings ago, but i am glad i met this herbal life saver. after i gave what was needed for Dr Mabuwa to prepare my herbal remedy and in 2 weeks after using i was instructed to go for a checkup and that was how i got healed without any traced of the disease in my body, i was tested Negative. Thanks you for you help sir, he cure others disease such as HIV, COLD SORES, DIABETES, HERPES VIRUS AND CANCER , You can reach him on Email: drmabuwasolutioncuretemple@gmail.com & What App/Call: +2348130714541 or visit his Website : drmabuwasolutioncuretemple.com or Web-page : https://drmabuwasolutioncuretemple.wordpress.com/contact

    ReplyDelete
  46. This is real take it serious, who will believe that a herbal can cure four years HERPES in my body, i never believe that this will work i have spend a lot when getting drugs from the hospital to keep me healthy, what i was waiting for is death because i was broke, one day i hard about this great man who is well know of HERPES and cancer cure, i decided to email him, unknowingly to me that this will be the end of the HERPES in my body, he prepare the herb for me, and give me instruction on how to take it, at the end of the two week, he told me to go to the hospital for a check up, and i went, surprisingly after the test the doctor confirm me negative, i thought it was a joke, i went to other hospital was also negative, then i took my friend who was also HERPES positive to the Dr, after the treatment she was also confirm negative . He also have the herb to cure cancer please i want every one with this virus to be free, that is why am dropping his email address, driyohasolutiontemple@yahoo.com and his contact +1 (407) 337-9869 do email him he is a great man. the government is also interested in this DR, thank you for saving my life, and I promise I will always testify for your good work .

    ReplyDelete
  47. Hello everyone am here to share my testimony. I was suffering from BREAST CANCER for the past 3 years and my Dr told me that there is nothing he could do, after the 5 times chemotherapy and radiation and i was not responding to treatment and not even getting better and i had no money for Surgery because it was too expensive for me. I was frustrated and confused, seeking advice from people until a friend told me about Dr. Osebulu Herbal Medicine and herbal cannabis oil and its fast curing ability of any kind of cancer and told me that her mother's LUNGS CANCER was cured by the same Doctor Osebulu. I was desperate to to have the HERBS and i contacted Dr. Osebulu via email to get the miraculous oil. The Dr send me the Herbal Medicine and Cannabis oil through FedEx, to cut the long story short, i got Completely Cured after taking the Herbs for a week. To cut the long story short, as i am writing this testimony on this Blog am so strong and healthy no more cancer in my body again. I did my test and the Doctor confirmed it, i do not have BREAST CANCER anymore which he (The Medical Doctor) was Shock when he confirmed it. I really want to Appreciate Dr Osebulu who got me cured with the help of his herbal medicine and to God Be All The Glory.

    He also have a herbal cure for the Following DISEASES and INFECTIONS below, this is 100% Real.

    -GENITAL WARTS
    -GENITAL AND ORAL HERPES
    -HPV
    -HIV
    -DIABETES
    -EPSTEIN BARR
    -PENIS ENLARGEMENT AND WEAK ERECTION
    -VIRGINA PROBLEM
    -WHOOPING COUGH
    - HEPATITIS A,B AND C
    -FORDYCE SPOT
    -COLD SORE
    -ALS
    -LOWER RESPIRATORY INFECTION
    -LOW SPERM COUNT
    -ZIKA VIRUS
    -COPD
    -STROKE
    -IMPOTENCE
    -PILE
    -HYPERTENSION
    -LOW SPERM COUNT
    -MENOPAUSE DISEASE
    -ASTHMA
    -BARENESS/INFERTILITY
    -PCOS
    -SHINGLES
    -VIRAL HEPATITIS/HEPATITIS B
    -FIBROID
    -ASTHMA
    -TOOTH PAIN
    -SICKLE CELL
    -TINNITUS
    -YEAST INFECTION
    -BARENESS/INFERTILITY
    -DIARRHEA and so on...


    EMAIL: drosebuluspellhome@hotmail.com

    Call/WhatsApp Dr. Osebulu Now: +2348083221034

    ReplyDelete
  48. Hello all viewer online HIV has cure but doctor said Hiv/Aids has no cure until i met Dr Zuku who help me in my life. I was infected with HIV/AIDS in 2006, i went to many hospitals for cure but there was no solution, so I was thinking how can I get a solution, so that my body can be okay. until this faithful day as i was browsing the net I saw a testimony on how Dr.Zuku helped people in curing HIV Disease, quickly I copied his Email which is drzukuspelltemple@gmail.com so i contacted him for solution for my HIV, so Dr.Zuku told me that his going to prepare herbal medicine for my health, then he prepared the medicine and luckily after two week my herpes was be cured. Dr Zuku is well recognize as one of the best herbalist doctor in Africa, you don't have to be sad anymore or share your tears anymore on this disease when the cure have already be found by Dr.Zuku herbal medicine, he so cure HERPES,CANCER, ALS,HEPATITIS B, DIABETIC ,or his Mobile number: +16177296273 or his Blogs https://drzukuspelltemple.blogspot.co.ke/ his website https://drzukuspelltemplewhereallkindsofproblemisbesolve.wordpress.com/contact/

    ReplyDelete
  49. The doctors said Herpes virus do not have medical cure because the virus is capable of hiding within the human cells, it remains protected from your immune system. Herpes isn’t a special virus – your immune system has the tools to fight it back. But because it is able to lay dormant in protected cells, your immune system is unable to remove it from your body,But with strong reactive herbal medication is capable of getting rid of the virus gradually and totally from your body without damaging any of your cells,natural herbs kills the virus totally not just reducing the out break. Get natural herbs cure from Dr Iyoha or reach him through his email: driyohasolutiontemple@yahoo.com or Call: +1 (407) 337-9869

    ReplyDelete
  50. I was cured of HIV with the used of natural herbs. My name is celina jolly and am from US. I love herbs so much. Most times, injection and drugs are just a waste of time. I was cured 8 months ago, i suffered from HIV for 13 yrs but with the help of Dr.Ogun herbal medicine, i was cured within few weeks of drinking the herbs he sent to me through courier delivery service. This same doctor also cured my Aunty from herpes, as soon as i heard she had herpes, i quickly refer her to Dr.Ogun and she was cured too after drinking his herbs.I have referred more than 15 persons to Dr.Ogun and they were all cured from their various illness. Have you taken herbs before?. You have spent so much money on drugs,injections,surgeries etc and yet you have no good result to show for it. Contact Dr. Ogun now, he is a herbalist doctor, i assured you of a cure if you drink his natural herbs. Dr.Ogun have herbs that cures Hiv, Herpes, diabetics, asthma, hepatitis, HBP, STD, cancer, chronic, etc. Contact Dr ogun through his Email address on: drogun62@gmail.com or WHATSAPP/CALL him on+2348104991149 . Please share the good news to other people once you are cured

    ReplyDelete
  51. I was cured of HIV with the used of natural herbs. My name is celina jolly and am from US. I love herbs so much. Most times, injection and drugs are just a waste of time. I was cured 8 months ago, i suffered from HIV for 13 yrs but with the help of Dr.Ogun herbal medicine, i was cured within few weeks of drinking the herbs he sent to me through courier delivery service. This same doctor also cured my Aunty from herpes, as soon as i heard she had herpes, i quickly refer her to Dr.Ogun and she was cured too after drinking his herbs.I have referred more than 15 persons to Dr.Ogun and they were all cured from their various illness. Have you taken herbs before?. You have spent so much money on drugs,injections,surgeries etc and yet you have no good result to show for it. Contact Dr. Ogun now, he is a herbalist doctor, i assured you of a cure if you drink his natural herbs. Dr.Ogun have herbs that cures Hiv, Herpes, diabetics, asthma, hepatitis, HBP, STD, cancer, chronic, etc. Contact Dr ogun through his Email address on: drogun62@gmail.com or WHATSAPP/CALL him on+2348104991149 . Please share the good news to other people once you are cured

    ReplyDelete
  52. Hello everyone. I was heartbroken because i had very small penis, not nice to satisfy a woman, i had so many relationship called off because of my situation, i have used so many product which i found online but none could offer me the help i searched for. i saw some few comments about this doctor called Dr. AMOS and I decided to email him on: Dramosehikioyaspelltemple@gmail.com so I decided to give his herbal product a try. i emailed him and he got back to me, he gave me some comforting words with his herbal cream for Penis Enlargement, Within 1 week of it, i began to feel the enlargement of my penis, " and now it just 2 weeks of using his products my penis is about 9 inches longer and strong. I'm so happy..feel free to contact DR AOS on his Email: Dramosehikioyaspelltemple@gmail.com or you can also call him on the whatsapp contact +2348103553159

    ReplyDelete
  53. I was cured of HIV with the used of natural herbs. My name is celina jolly and am from US. I love herbs so much. Most times, injection and drugs are just a waste of time. I was cured 8 months ago, i suffered from HIV for 13 yrs but with the help of Dr.Ogun herbal medicine, i was cured within few weeks of drinking the herbs he sent to me through courier delivery service. This same doctor also cured my Aunty from herpes, as soon as i heard she had herpes, i quickly refer her to Dr.Ogun and she was cured too after drinking his herbs.I have referred more than 15 persons to Dr.Ogun and they were all cured from their various illness. Have you taken herbs before?. You have spent so much money on drugs,injections,surgeries etc and yet you have no good result to show for it. Contact Dr. Ogun now, he is a herbalist doctor, i assured you of a cure if you drink his natural herbs. Dr.Ogun have herbs that cures Hiv, Herpes, diabetics, asthma, hepatitis, HBP, STD, cancer, chronic, etc. Contact Dr ogun through his Email address on: drogun62@gmail.com or WHATSAPP/CALL him on+2348104991149 . Please share the good news to other people once you are cured

    ReplyDelete
  54. Been diagnosed of herpes is just like been through hell but everything is possible.So amazing and i want to testify of the good work done by DR EREDIAWA, very strong Herbal Doc.DR EREDIAWA has proved science and scientists wrong for believing there is know cure for Herpes Virus but to be sincere this DR EREDIAWA,is real and powerful,i never thought this cure will work for good,this great Doc has proof to me and it has worked and still working perfectly.I,m Marian Clem,from Alabama,USA.i was diagnosed of the deadly disease called HERPES SIMPLEX VIRUS,19th,March,2017.I try talking a lot of drugs nor work for good,my Doc told me there is know cure that i can only take valacyclovir,famciclovir,acyclovir and when there is any outbreak i do use penciclovir cream,yet nor work for good,i thought this will be the end and all hope was lost,Speaking to anyone was a problem because i was so worried and always in the state of unrest,i thought it was over until this day i was searching for help here on the internet,i came across a testimony about DR EREDIAWA,on how he uses his Natural ROOTS AND HERBS to cure different Disease,At first i thought it was all a lie,i decided to give it a try since there was know option when i contacted DR EREDIAWA OKOH, he told me he will get me cure of my Disease,i was still in doubt and he ask me few questions and gave me form to fill which I did,his told me he will need to prepare the herbal medication for me to apply and once that is done he will spend it down to me via:courier delivery service which he did and instructed me on what to eat and do during this period within two days he sent a parcel to me through the courier delivery service. it was the ROOTS and a pure HERBS, as described by Doc I took the ROOTS and HERBS within twenty four days,my body system was already balance he told me to run a test,So i went to the hospital for the test, it was so amazing,awesome and exciting what seems to be impossible became possible,the virus disappeared completely from my system quickly I called him and told him the result,he congratulated me.Today i am a happy person again,Don’t you think this testimony is worth sharing? I promise to tell the world about his NATURAL ROOTS AND HERBS,I,m sharing this testimony because many has died of HERPES and a lot of disease, i just want the world to know there is cure to that illness or Disease you are suffering from.Contacting him on his email address at drerediawaherbs@gmail.com or you can message him on his via whatsApp Number +2348159412586

    ReplyDelete
  55. hello everyone this is real and i want to tell the whole world about
    how DR OSCAR HERBAL CREAM and LIQUID helped me enlarge my penis size,
    i have been trying since 23 years of age to enlarge my penis but none rendered
    me the help i want i have used vaccine ,penis pump,surgery,online creams
    from USA SAMOA,CANADA CAMBODIA and more but none of them enlarge my penis
    i was really frustrated and tired of living because my penis was too small
    ,imagine a cute and handsome man of 38 years old like me having 3.5 inches
    and to make it worse i was having erectile dysfunction which was so annoying
    to me,my girlfriends have left me because of my small penis ....to GOD be the
    glory as i was searching through the online for help on a facebook page i saw
    one Mr john from USA testifying of how DR OSCAR HERBAL CREAM and LIQUID enlarge
    his penis from 3 inches to 10 inches within two weeks of using his herbal cream..
    so i quickly contacted him through his email droscarenlargementhome@yahoo.com and
    message him and he replied me and gave me comforting words and He told me all i
    need to do and i was surprise after one week of using his cream my penis enlarge to
    7 inches and is now 10 inches long and very thicker i am so happy to feel like a real
    man in the bedroom at last so if you need penis enlargement,breast enlargement,weak
    erection,erectile dysfunction cure and many sexual relation cure do not hesitate to
    email him now on droscarenlargementhome@yahoo.com

    ReplyDelete

  56. Am Lane from Spain, am here to talk about this wonderful doc Alex. who deals in herbal medicine, hes a great man with wisdom .i had issues with my penis length. am always weak in sex. i cant satisfy my woman, she always ask for divorce. i did all my best to give a happy life with my kids, but she always insult me. still i met this doc and he instruct me on what to do. i obey him and got his medicine through DHL, delivery service. after using this product my sex life is awesome, wow you all on same problem got to mail him via..alexherbalsolutionhome@gmail.com or alexherbalsolutionhome@yahoo.com you can also whats app. +2349068579934.

    he attends to lots of problems. etc good luck

    herpes treatment,
    pregnancy solution
    HIV cure. indeed this man is sent from god.

    Good Luck

    ReplyDelete
  57. I'm lenda tanny , I contracted HIV disease in 2016, I was told by my doctor that there's no possible cure for HIV. I started taking my ARV's, My CD4 was 77 and viral load was 112,450. I saw an email of Dr.Bello , also I saw a lot of testimonials about him on how he uses herbal medicine to cure HIV disease. I contacted him and told him my problems, He sent me the herbal medicine and I took it for 7 days after then I went for check-up and I was tested negative. The medicine has NO SIDE EFFECT, there's no special diet when taking the medicine. He also cure ALS, HEPATITIS B, CANCER, HERPES, DIABETES and lots more.You can reach him on bellospelltemple@gmail.com or call, whatsApp him on +2348147271779.

    ReplyDelete
  58. Hello everyone am here to share my testimony. I was suffering from BREAST CANCER for the past 3 years and my Dr told me that there is nothing he could do, after the 5 times chemotherapy and radiation and i was not responding to treatment and not even getting better and i had no money for Surgery because it was too expensive for me. I was frustrated and confused, seeking advice from people until a friend told me about Dr. Osebulu Herbal Medicine and herbal cannabis oil and its fast curing ability of any kind of cancer and told me that her mother's LUNGS CANCER was cured by the same Doctor Osebulu. I was desperate to to have the HERBS and i contacted Dr. Osebulu via email to get the miraculous oil. The Dr send me the Herbal Medicine and Cannabis oil through FedEx, to cut the long story short, i got Completely Cured after taking the Herbs for a week. To cut the long story short, as i am writing this testimony on this Blog am so strong and healthy no more cancer in my body again. I did my test and the Doctor confirmed it, i do not have BREAST CANCER anymore which he (The Medical Doctor) was Shock when he confirmed it. I really want to Appreciate Dr Osebulu who got me cured with the help of his herbal medicine and to God Be All The Glory.

    He also have a herbal cure for the Following DISEASES and INFECTIONS below, this is 100% Real.

    -GENITAL WARTS
    -GENITAL AND ORAL HERPES
    -HIV
    -DIABETES
    -PENIS ENLARGEMENT AND WEAK ERECTION
    -VIRGINA PROBLEM
    -WHOOPING COUGH
    -STROKE
    -PILE
    -LOW SPERM COUNT
    -ASTHMA
    -FIBROID
    -TOOTH PAIN
    -BARENESS/INFERTILITY
    -DIARRHEA and so on...


    EMAIL: drosebuluspellhome@hotmail.com

    Call/WhatsApp Dr. Osebulu Now: +2348083221034

    ReplyDelete