Jewett HJ, Eversole Jr. SL. Carcinoma of the Bladder: Characteristic Modes of Local Invasion. J Urol. 1960. 83;4:383-89.
This 1960 manuscript is the transcript of a talk given by Dr. Jewett at the 1960 Annual Meeting of the American Association of Genitourinary Surgeons. Drs. Jewett and Eversole review the pathology from 303 infiltrating bladder cancers and made the following observations.
Jewett and Eversole arrived at three "characteristic modes of local invasion" in bladder cancer:
"1) as a fairly compact mass (70%)
2) as finger-like projections represented frequently as isolated masses (27%)
3) as intramural lymphatic metastases traveling in a direction more or less perpendicular to the plane of the overlying bladder mucosa (3%)"
To reach these conclusions, Jewett and Eversole first characterized the 300 specimens (from autopsy, cystectomy and transurethral resections) using Jewett's staging system: A, submucosa only; B1, less than halfway through the muscle; B2, halfway or more through the muscle; C, perivesical fat or prostate. They immediately found that the majority of cases of lymphatic invasion were stage B2 or C. In addition, well-differentiated tumors (low-grade) remained low-stage; and poorly differentiated, squamous and anaplastic tumor types were much more likely to reach the lymphatics at earlier-stages.
Using these observations, Jewett and Eversole looked closely at pathologic specimens to determine modes on invasion. They determined that many of the "early-stage" tumors were actually missed invasive tumors that invaded deeply into the bladder lymphatics as finger-like projections or perpendicularly into the bladder wall – both difficult to assess with the constraints of serial sectioning and two-dimensional pathologic analysis. While these finger-like and perpendicular growth patterns were relatively uncommon, they were more common in deeply invasive tumors (Stage B2 and C).
To read the entire manuscript: follow the link above, visit the Centennial Website or click here.
HISTORICAL CONTRIBUTIONS highlight the greatest academic manuscripts from the Brady Urological Institute over the past 100 years. As the Brady Urological Institute approaches its centennial, we will present a HISTORICAL CONTRIBUTION from each of the past 100 years. In the most recent experience, the most highly cited article from each year is selected; older manuscripts were selected based on their perceived impact on the field. We hope you enjoy!
CURE YOUR SICKNESS AND DISEASE WITH HERBAL CURE FROM AFRICA.ReplyDelete
Are you in pains or can not find cure for your sickness or disease? Wipe your tears, we are here to cure you of whatever disease or sickness you are battling right now.
We specialize in all kind of treatment and with the help of Almighty God you will be well again, hurry now and contact us via email: email@example.com
HEALTH IS WEALTH.
I'm very excited to inform everyone that I'm completely cured from my HSV 1&2 recently. I have used Oregano oil, Coconut oil, Acyclovir, Val acyclovir, Famciclovir , and some other products and it's really help during my outbreaks but I totally got cured from my HSV 2 with a strong and active herbal medicine ordered from a powerful herbalist and it completely fought the virus from my nervous system and I was tested negative after three weeks of usage. I'm here to let y'all know that HSV 1& 2 has a complete cure, I got rid of mine with the help of Dr Moses Buba and his herbal exploit, AFTER I engage with other wrong doctors. Contact him via email: firstname.lastname@example.org or Call/WhatsApp him at +2349060529305Delete
Get rid of Cold Sores, unexpected Outbreak and HSV, HSV1, HSV2 and all kinds of Viruses infections with antiviral roots and herbs herbal medicine which is purely Natural, no side effects? don't have to keep waiting for treatment when the is a herbal medicine that Eradicate this Viruses. I was searching online for Herbal Cure for Herpes Virus when I saw a testimony online about Dr. Akintunde and how he cured a lady of HSV1 with his.ReplyDelete
natural herbal medicine and tested Negative and in less than a month she was cured of this virus. So it took me time to believe that this was true, because my family Doctor tried all his best to get rid of this virus in my body system but yet no cure and I suffered from outbreak and Cold Sores always. I had to contact Dr. Akintunde after I have access his website and i had faith in God that I was going to be fine and free of this virus one day. Finally I contacted Dr. Akintunde on his WhatsApp number that I saw on the testimony post online, and after our conversation the Doctor only promise me that I was going to be cured and free of this virus after taking his natural herbal medicine because I was tired of my situation with this virus it was so distracting to my life and whole family. Later Dr. Akintunde send some Herbal medicine to me through UPS courier service, with instructions on how to used this medicine, to my biggest surprise first week of taking my herbal medication I saw great improvement and I still think that it's a dream but this is real, I now test Negative of this virus today and my blood pressure well regulated now, my family doctor after my test was extremely surprise to see my test result change to HSV1 Negative and no more symptoms, cold sores, sores throat and outbreak again. I wish to tell everyone about this, mostly if you have this virus then do yourself good to contact Dr. Akintunde and see what the Lord can do through this Herbal Doctor's medicine in less than a month. 100% free from herpes Virus. I and my family say "thank you" Sir, for helping my life. You are a blessing to this generation and God will reward you richly
WhatsApp number: +234 703 524 5593
MY DAUGHTER CANCER HEALING TESTIMONEYDelete
Hi everyone, this is good news, a perfect and greats one. My daughter of
17years who has suffered of Colon Cancer Stage for 2 and half years has been
cure by a Herbal doctor called Dr voodoo, who uses herbal and traditional
medicine to cure people. I have spent so much on my daughter's health for
years but no improvement. A friend told me about this herbal man who cure
people with herbal medicine. he cures all sickness, diseases, viruses, and
infections with his different herbal curing medicine.The result that
declares my daughter janet healed was from a hospital here in USA, And the
results of the test says my daughter was okay. Dr voodoo directed that
janet would be heal in 7days if she uses the medicine as directed. And
7days later, we went to confirm from the central hospital and several test
that was done says my daughter is not sick or anything. So she was cured by
this herbal doctor in 7days. This amaze me though. I would advice everyone
to meet this Dr voodoo his email is email@example.com
for his herbal medicine to cure your illness because am happy to see my
daughter healthy again.Meet Dr voodoo and set yourself and your love ones
will free you can also add Dr voodoo on whatsApp +2348140120719
من أفضل المقالات على الإطلاق صراحة تستحق التعمق أكثر واكثر لقد سعدت بقراءة مقالك وانا فخور بك وبما تقدمه في مدونتك ف انت مثال للمدونات العربية التي تقدم محتوي مفيدReplyDelete
شركة تصميم مواقع
I am here to give my testimony about chief dr lucky who helped me in my life, i want to inform the public how i was cured from herpes simplex virus by chief dr lucky, i visited different hospital but they gave me list of drugs like Famvir, Zovirax, and Valtrex which is very expensive to treat the symptoms and never cured me. I was browsing through the Internet searching for remedy on herpes and i saw comment of people talking about how chief dr lucky cured them. when i contacted him he gave me hope and send a Herbal medicine to me that i took and it seriously worked for me, am a free person now without problem, my herpes result came out negative. I pray for you chief dr lucky am cured you can also get your self cured my friends if you really need my doctor help, you can reach him now.ReplyDelete
Email: firstname.lastname@example.org Call or What's App +2348132777335
Website : http://chiefdrluckysolutionhome.website2.me/
supreme new york
kevin durant shoes
michael jordan shoes
kyrie irving shoes
I was diagnosed as HEPATITIS B carrier in 2013 with fibrosis of theReplyDelete
liver already present. I started on antiviral medications which
reduced the viral load initially. After a couple of years the virus
became resistant. I started on HEPATITIS B Herbal treatment from
ULTIMATE LIFE CLINIC (www.ultimatelifeclinic.com) in March, 2020. Their
treatment totally reversed the virus. I did another blood test after
the 6 months long treatment and tested negative to the virus. Amazing
treatment! This treatment is a breakthrough for all HBV carriers.
suivant Dior Dolabuy voir le site Web répliques de sacs ysl supplémentaire lecture dolabuy.coReplyDelete